Cell Culture
Apps.CellCultivation History
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Sample Results
Input
- (:html:)<a href="/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
Predictions
- (:html:)<a href="/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
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(:title Cell Culture:) (:keywords nonlinear, model, predictive control, APMonitor, differential, algebraic, modeling language, cell culture:) (:description Simulation of a cell culture with APMonitor:)
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- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
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- (:html:)<a href="/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
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- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
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- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
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- (:html:)<a href="/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
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(:html:)<pre>
APMonitor Modeling Language
https://www.apmonitor.com
Cultivation of isolated plant cells in suspension culture
Munack A., Posten C. (1989): Design of optimal dynamical experiments for
parameter estimation, Proceedings of the Americal Control Conference,
Vol. 4, 2010-2016.
Model cells
Parameters romax = 85 yco = 0.897 ypx = 0.0673 vl = 1 kl = 0.0137 os = 86.2 rsmax = 0.0352 ks = 0.186 ko = 6.32 yxs = 5.6 mum = 0.118 rf = 0.05 End Parameters Variables x = 4 s = 50 p = 5 o = 0.022 c = 1.059 End Variables Intermediates rs = rsmax * s / (ks + s) mu = yxs*rs - mum ro = romax * o / (ko + o) rc = yco*ro End Intermediates Equations $x = mu * x $s = -rs*x + 10*rf $p = ypx*mu*x ro * x = (os - o)*kl*vl c = rc * x / vl End Equations
End Model </pre>(:htmlend:)
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- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
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- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
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